A new study reveals that many people with cancer use marijuana, and rates of use in the U.S. have increased over time. [...]

The U.S. Food and Drug Administration today granted final approval of the first generic naloxone hydrochloride nasal spray, commonly known as Narcan, a life-saving medication that can stop or reverse the effects of an opioid overdose. [...]

Patients prescribed opioid pain medications whose doses varied over time were 3 times more likely to experience an overdose than patients prescribed stable opioid doses, according to an observational study from Kaiser Permanente published today in JAMA Network Open. [...]

Go to Google and type: "leading cause of accidental death in ..." Then type in a state -- any state in central Appalachia -- and hit search. The answer is the same: opioid overdoses and drug poisoning lead the way in fatalities in these states, far above former front-runners, such as car a [...]

The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors today approved $44.6 million to fund 12 studies comparing the best ways to treat a range of health conditions that impose high burdens on patients, caregivers and the healthcare system. [...]

Targets to eliminate pain after surgery have driven increases in the use of opioids, and are a major cause of the opioid crisis in the USA, Canada and other countries. [...]

The U.S. CDC has issued a letter clarifying that people suffering from severe pain caused by cancer or sickle-cell anemia should not be denied prescriptions for opioid pain-killers. [...]

Substance use disorders continue to rise at alarming rates among adolescents, with opioid abuse contributing to this significant public health problem. [...]

Understanding the interactions between alcohol and cannabis can provide researchers, clinicians and other HCPs with important information on the severity of their side effects. [...]

Ohio, West Virginia, and the District of Columbia have the highest disparity between opioid-related deaths and access to treatment providers for opioid use disorder in the U.S. [...]